Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	INVS	HGNC:17870 (HGNC) 27130 (Entrez Gene) 243305 (OMIM) INVS (Alliance of Genome Resources)	Chr9 q31.1	Chr9:100099243-100302175 (+) GRCh38	hypertension nephronophthisis 2	Q9Y283 (UniProt | EBI) NM_014425 (RefSeq)
mouse	Invs	MGI:1335082 (MGI) 16348 (Entrez Gene) Gene Tree Invs (Alliance of Genome Resources)	Chr4 26.11 cM	Chr4:48279760-48431954 (+) GRCm39	nephronophthisis 2 tetralogy of Fallot	ENSMUSG00000028344 (Ensembl Gene Model) ENSMUSP00000030029 (Ensembl) ENSMUST00000030029 (Ensembl)
rat	Invs	RGD:1563359 (Rat Genome Database) 313228 (Entrez Gene) Invs (Alliance of Genome Resources)	Chr5 q22			NP_001101402 (RefSeq) NM_001107932 (RefSeq)
zebrafish	invs	ZDB-GENE-020507-2 (Zebrafish Model Organism Database) 245946 (Entrez Gene) invs (Alliance of Genome Resources)	Chr16			Q8UVC1 (UniProt | EBI) NM_152970 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.