Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTGS1	HGNC:9604 (HGNC) 5742 (Entrez Gene) 176805 (OMIM) PTGS1 (Alliance of Genome Resources)	Chr9 q33.2	Chr9:122370530-122395703 (+) GRCh38		P23219 (UniProt | EBI) NM_000962 (RefSeq)
mouse	Ptgs1	MGI:97797 (MGI) 19224 (Entrez Gene) Gene Tree Ptgs1 (Alliance of Genome Resources)	Chr2 24.19 cM	Chr2:36120438-36142284 (+) GRCm39	pre-eclampsia	ENSMUSG00000047250 (Ensembl Gene Model) ENSMUSP00000059977 (Ensembl) ENSMUST00000062069 (Ensembl)
rat	Ptgs1	RGD:3439 (Rat Genome Database) 24693 (Entrez Gene) Ptgs1 (Alliance of Genome Resources)	Chr3 p11			Q63921 (UniProt | EBI) NM_017043 (RefSeq)
zebrafish	ptgs1	ZDB-GENE-020530-1 (Zebrafish Model Organism Database) 246226 (Entrez Gene) ptgs1 (Alliance of Genome Resources)	Chr5			NP_705942 (RefSeq) NM_153656 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.