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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PTGS2 HGNC:9605 (HGNC)
5743 (Entrez Gene)
600262 (OMIM)
PTGS2 (Alliance of Genome Resources)
Chr1 q31.1 Chr1:186671791-186680922 (-)
GRCh38
arteriosclerosis
asthma
avian influenza
cardiovascular system disease
chronic obstructive pulmonary disease
cystic fibrosis
esophagitis
hepatocellular carcinoma
idiopathic pulmonary fibrosis
liver cirrhosis
lung non-small cell carcinoma
myocardial infarction
osteoarthritis
pancreatic cancer
prostate cancer
pulmonary fibrosis
rheumatoid arthritis
sarcoidosis
urinary bladder cancer
P35354 (UniProt | EBI)
NM_000963 (RefSeq)
mouse Ptgs2 MGI:97798 (MGI)
19225 (Entrez Gene)
Gene Tree
Ptgs2 (Alliance of Genome Resources)
Chr1 63.84 cM Chr1:149975851-149983978 (+)
GRCm39
19225 (NCBI Gene Model)
Q05769 (UniProt | EBI)
NM_011198 (RefSeq)
rat Ptgs2 RGD:620349 (Rat Genome Database)
29527 (Entrez Gene)
Ptgs2 (Alliance of Genome Resources)
Chr13 q21 P35355 (UniProt | EBI)
NM_017232 (RefSeq)
zebrafish ptgs2a ZDB-GENE-020530-2 (Zebrafish Model Organism Database)
246227 (Entrez Gene)
ptgs2a (Alliance of Genome Resources)
Chr2 NP_705943 (RefSeq)
NM_153657 (RefSeq)
ptgs2b ZDB-GENE-041014-323 (Zebrafish Model Organism Database)
559020 (Entrez Gene)
ptgs2b (Alliance of Genome Resources)
Chr20 NP_001020675 (RefSeq)
NM_001025504 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory