Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SIM1	HGNC:10882 (HGNC) 6492 (Entrez Gene) 603128 (OMIM) SIM1 (Alliance of Genome Resources)	Chr6 q16.3	Chr6:100385009-100464921 (-) GRCh38	obesity	P81133 (UniProt | EBI) NM_001374769 (RefSeq)
mouse	Sim1	MGI:98306 (MGI) 20464 (Entrez Gene) Gene Tree Sim1 (Alliance of Genome Resources)	Chr10 24.87 cM	Chr10:50770850-50865248 (+) GRCm39	obesity	ENSMUSG00000019913 (Ensembl Gene Model) ENSMUSP00000020071 (Ensembl) ENSMUST00000020071 (Ensembl)
rat	Sim1	RGD:1309949 (Rat Genome Database) 309888 (Entrez Gene) Sim1 (Alliance of Genome Resources)	Chr20 q13			NP_001101111 (RefSeq) NM_001107641 (RefSeq)
zebrafish	sim1a	ZDB-GENE-020829-1 (Zebrafish Model Organism Database) 260351 (Entrez Gene) sim1a (Alliance of Genome Resources)	Chr16			Q98SJ5 (UniProt | EBI) NM_178222 (RefSeq)
	sim1b	ZDB-GENE-041210-5 (Zebrafish Model Organism Database) 566656 (Entrez Gene) sim1b (Alliance of Genome Resources)	Chr4			NP_001153057 (RefSeq) NM_001159585 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.