Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLX3	HGNC:13532 (HGNC) 30012 (Entrez Gene) 604640 (OMIM) TLX3 (Alliance of Genome Resources)	Chr5 q35.1	Chr5:171309248-171312139 (+) GRCh38		O43711 (UniProt | EBI) NM_021025 (RefSeq)
mouse	Tlx3	MGI:1351209 (MGI) 27140 (Entrez Gene) Gene Tree Tlx3 (Alliance of Genome Resources)	Chr11 19.21 cM	Chr11:33150752-33153589 (-) GRCm39	congenital central hypoventilation syndrome	ENSMUSG00000040610 (Ensembl Gene Model) ENSMUSP00000047457 (Ensembl) ENSMUST00000037746 (Ensembl)
rat	Tlx3	RGD:1564190 (Rat Genome Database) 497881 (Entrez Gene) Tlx3 (Alliance of Genome Resources)	Chr10 q12			NP_001414519 (RefSeq) NM_001427590 (RefSeq)
zebrafish	tlx3b	ZDB-GENE-021021-1 (Zebrafish Model Organism Database) 266965 (Entrez Gene) tlx3b (Alliance of Genome Resources)	Chr10			NP_739572 (RefSeq) NM_170766 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.