Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NPM1	HGNC:7910 (HGNC) 4869 (Entrez Gene) 164040 (OMIM) NPM1 (Alliance of Genome Resources)	Chr5 q35.1	Chr5:171387116-171411810 (+) GRCh38	acute myeloid leukemia	P06748 (UniProt | EBI) NM_001355010 (RefSeq)
mouse	Npm1	MGI:106184 (MGI) 18148 (Entrez Gene) Gene Tree Npm1 (Alliance of Genome Resources)	Chr11 19.21 cM	Chr11:33102287-33113206 (-) GRCm39	myelodysplastic syndrome	ENSMUSG00000057113 (Ensembl Gene Model) ENSMUSP00000075067 (Ensembl) ENSMUST00000075641 (Ensembl)
rat	Npm1	RGD:3192 (Rat Genome Database) 25498 (Entrez Gene) Npm1 (Alliance of Genome Resources)	Chr10 q12			P13084 (UniProt | EBI) NM_012992 (RefSeq)
zebrafish	npm1a	ZDB-GENE-021028-1 (Zebrafish Model Organism Database) 266985 (Entrez Gene) npm1a (Alliance of Genome Resources)	Chr10			NP_955460 (RefSeq) NM_199428 (RefSeq)
	npm1b	ZDB-GENE-080723-7 (Zebrafish Model Organism Database) 553507 (Entrez Gene) npm1b (Alliance of Genome Resources)	Chr14			NP_001159627 (RefSeq) NM_001166155 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.