Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TTN	HGNC:12403 (HGNC) 7273 (Entrez Gene) 188840 (OMIM) TTN (Alliance of Genome Resources)	Chr2 q31.2	Chr2:178525989-178830802 (-) GRCh38	autosomal recessive limb-girdle muscular dystrophy type 2J congenital myopathy 5 dilated cardiomyopathy dilated cardiomyopathy 1G hypertrophic cardiomyopathy 9 myofibrillar myopathy 9 tibial muscular dystrophy	Q8WZ42 (UniProt | EBI) NM_001256850 (RefSeq)
mouse	Ttn	MGI:98864 (MGI) 22138 (Entrez Gene) Gene Tree Ttn (Alliance of Genome Resources)	Chr2 45.13 cM	Chr2:76534324-76812891 (-) GRCm39	autosomal recessive limb-girdle muscular dystrophy type 2J dilated cardiomyopathy 1G tibial muscular dystrophy	ENSMUSG00000051747 (Ensembl Gene Model) ENSMUSP00000097561 (Ensembl) ENSMUST00000099981 (Ensembl)
zebrafish	ttn.1	ZDB-GENE-030616-413 (Zebrafish Model Organism Database) 100001684 (Entrez Gene) ttn.1 (Alliance of Genome Resources)	Chr9			XP_068079596 (RefSeq) NM_207183 (RefSeq)
	ttn.2	ZDB-GENE-030113-2 (Zebrafish Model Organism Database) 317731 (Entrez Gene) ttn.2 (Alliance of Genome Resources)	Chr9			XP_068079594 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.