Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRKAR2A	HGNC:9391 (HGNC) 5576 (Entrez Gene) 176910 (OMIM) PRKAR2A (Alliance of Genome Resources)	Chr3 p21.31	Chr3:48744591-48847874 (-) GRCh38	congestive heart failure	P13861 (UniProt | EBI) NM_001321989 (RefSeq)
mouse	Prkar2a	MGI:108025 (MGI) 19087 (Entrez Gene) Gene Tree Prkar2a (Alliance of Genome Resources)	Chr9 59.63 cM	Chr9:108569342-108627643 (+) GRCm39		19087 (NCBI Gene Model) P12367 (UniProt | EBI) NM_008924 (RefSeq)
rat	Prkar2a	RGD:3393 (Rat Genome Database) 29699 (Entrez Gene) Prkar2a (Alliance of Genome Resources)	Chr8 q32			P12368 (UniProt | EBI) NM_019264 (RefSeq)
zebrafish	prkar2aa	ZDB-GENE-030131-1007 (Zebrafish Model Organism Database) 556042 (Entrez Gene) prkar2aa (Alliance of Genome Resources)	Chr8			NP_001070838 (RefSeq) NM_001077370 (RefSeq)
	prkar2ab	ZDB-GENE-040426-2427 (Zebrafish Model Organism Database) 405894 (Entrez Gene) prkar2ab (Alliance of Genome Resources)	Chr22			NP_998123 (RefSeq) NM_212958 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.