Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PIK3R1	HGNC:8979 (HGNC) 5295 (Entrez Gene) 171833 (OMIM) PIK3R1 (Alliance of Genome Resources)	Chr5 q13.1	Chr5:68215740-68301821 (+) GRCh38	agammaglobulinemia 7 Alzheimer's disease astroblastoma endometrial adenocarcinoma endometrial cancer endometrial carcinoma immunodeficiency 36 lung small cell carcinoma SHORT syndrome type 2 diabetes mellitus	P27986 (UniProt | EBI) NM_181504 (RefSeq)
mouse	Pik3r1	MGI:97583 (MGI) 18708 (Entrez Gene) Gene Tree Pik3r1 (Alliance of Genome Resources)	Chr13 53.92 cM	Chr13:101817269-101904725 (-) GRCm39	SHORT syndrome X-linked agammaglobulinemia	18708 (NCBI Gene Model) P26450 (UniProt | EBI) NM_001077495 (RefSeq)
rat	Pik3r1	RGD:3329 (Rat Genome Database) 25513 (Entrez Gene) Pik3r1 (Alliance of Genome Resources)	Chr2 q12			Q63787 (UniProt | EBI) NM_013005 (RefSeq)
zebrafish	pik3r1	ZDB-GENE-030131-1280 (Zebrafish Model Organism Database) 557176 (Entrez Gene) pik3r1 (Alliance of Genome Resources)	Chr5			NP_001268773 (RefSeq) NM_001281844 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.