Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FLNA	HGNC:3754 (HGNC) 2316 (Entrez Gene) 300017 (OMIM) FLNA (Alliance of Genome Resources)	ChrX q28	ChrX:154348524-154374634 (-) GRCh38	craniosynostosis frontometaphyseal dysplasia 1 Melnick-Needles syndrome mitral valve prolapse osteochondrodysplasia otopalatodigital syndrome spectrum disorder otopalatodigital syndrome type 1 otopalatodigital syndrome type 2 periventricular nodular heterotopia terminal osseous dysplasia X-linked cardiac valvular dysplasia X-linked chronic idiopathic intestinal pseudo-obstruction	P21333 (UniProt | EBI) NM_001110556 (RefSeq)
mouse	Flna	MGI:95556 (MGI) 192176 (Entrez Gene) Gene Tree Flna (Alliance of Genome Resources)	ChrX 37.89 cM	ChrX:73267067-73293426 (-) GRCm39	periventricular nodular heterotopia	ENSMUSG00000031328 (Ensembl Gene Model) ENSMUSP00000033699 (Ensembl) ENSMUST00000033699 (Ensembl)
rat	Flna	RGD:1560614 (Rat Genome Database) 293860 (Entrez Gene) Flna (Alliance of Genome Resources)	ChrX			NP_001128071 (RefSeq) NM_001134599 (RefSeq)
zebrafish	flna	ZDB-GENE-030131-2145 (Zebrafish Model Organism Database) 562529 (Entrez Gene) flna (Alliance of Genome Resources)	Chr23			XP_021329297 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.