Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITM2B	HGNC:6174 (HGNC) 9445 (Entrez Gene) 603904 (OMIM) ITM2B (Alliance of Genome Resources)	Chr13 q14.2	Chr13:48232612-48270357 (+) GRCh38	ITM2B-related cerebral amyloid angiopathy 1 ITM2B-related cerebral amyloid angiopathy 2	Q9Y287 (UniProt | EBI) NM_021999 (RefSeq)
mouse	Itm2b	MGI:1309517 (MGI) 16432 (Entrez Gene) Gene Tree Itm2b (Alliance of Genome Resources)	Chr14 38.88 cM	Chr14:73599666-73622729 (-) GRCm39	cerebral amyloid angiopathy	16432 (NCBI Gene Model) O89051 (UniProt | EBI) NM_008410 (RefSeq)
rat	Itm2b	RGD:620727 (Rat Genome Database) 290364 (Entrez Gene) Itm2b (Alliance of Genome Resources)	Chr15 q11			Q5XIE8 (UniProt | EBI) NM_001006963 (RefSeq)
zebrafish	itm2ba	ZDB-GENE-030131-2352 (Zebrafish Model Organism Database) 323632 (Entrez Gene) itm2ba (Alliance of Genome Resources)	Chr6			NP_955940 (RefSeq) NM_199646 (RefSeq)
	itm2bb	ZDB-GENE-040426-2139 (Zebrafish Model Organism Database) 406248 (Entrez Gene) itm2bb (Alliance of Genome Resources)	Chr9			NP_998141 (RefSeq) NM_212976 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.