Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADRA1A	HGNC:277 (HGNC) 148 (Entrez Gene) 104221 (OMIM) ADRA1A (Alliance of Genome Resources)	Chr8 p21.2	Chr8:26748150-26867379 (-) GRCh38	Alzheimer's disease heroin dependence hypertension	P35348 (UniProt | EBI) NM_001322504 (RefSeq)
mouse	Adra1a	MGI:104773 (MGI) 11549 (Entrez Gene) Gene Tree Adra1a (Alliance of Genome Resources)	Chr14 34.6 cM	Chr14:66872700-67008617 (+) GRCm39		ENSMUSG00000045875 (Ensembl Gene Model) ENSMUSP00000125354 (Ensembl) ENSMUST00000161339 (Ensembl)
rat	Adra1a	RGD:2055 (Rat Genome Database) 29412 (Entrez Gene) Adra1a (Alliance of Genome Resources)	Chr15 p12			P43140 (UniProt | EBI) NM_017191 (RefSeq)
zebrafish	adra1aa	ZDB-GENE-030131-2831 (Zebrafish Model Organism Database) 798498 (Entrez Gene) adra1aa (Alliance of Genome Resources)	Chr8			NP_001311383 (RefSeq) NM_001324454 (RefSeq)
	adra1ab	ZDB-GENE-060503-384 (Zebrafish Model Organism Database) 557259 (Entrez Gene) adra1ab (Alliance of Genome Resources)	Chr10			XP_685389 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.