Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CUL3	HGNC:2553 (HGNC) 8452 (Entrez Gene) 603136 (OMIM) CUL3 (Alliance of Genome Resources)	Chr2 q36.2	Chr2:224470150-224585397 (-) GRCh38	pseudohypoaldosteronism	Q13618 (UniProt | EBI) NM_003590 (RefSeq)
mouse	Cul3	MGI:1347360 (MGI) 26554 (Entrez Gene) Gene Tree Cul3 (Alliance of Genome Resources)	Chr1 41.24 cM	Chr1:80242640-80318197 (-) GRCm39		ENSMUSG00000004364 (Ensembl Gene Model) ENSMUSP00000130738 (Ensembl) ENSMUST00000163119 (Ensembl)
rat	Cul3	RGD:1308190 (Rat Genome Database) 301555 (Entrez Gene) Cul3 (Alliance of Genome Resources)	Chr9 q34			B5DF89 (UniProt | EBI) NM_001106923 (RefSeq)
zebrafish	cul3a	ZDB-GENE-030131-3376 (Zebrafish Model Organism Database) 324655 (Entrez Gene) cul3a (Alliance of Genome Resources)	Chr2			NP_955985 (RefSeq) NM_199691 (RefSeq)
	cul3b	ZDB-GENE-081007-1 (Zebrafish Model Organism Database) 572370 (Entrez Gene) cul3b (Alliance of Genome Resources)	Chr15			NP_001177414 (RefSeq) NM_001190485 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.