Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TSC1	HGNC:12362 (HGNC) 7248 (Entrez Gene) 605284 (OMIM) TSC1 (Alliance of Genome Resources)	Chr9 q34.13	Chr9:132891348-132946874 (-) GRCh38	intellectual disability lymphangioleiomyomatosis tuberous sclerosis tuberous sclerosis 1	Q92574 (UniProt | EBI) NM_001406622 (RefSeq)
mouse	Tsc1	MGI:1929183 (MGI) 64930 (Entrez Gene) Gene Tree Tsc1 (Alliance of Genome Resources)	Chr2 19.38 cM	Chr2:28531240-28581179 (+) GRCm39	anterior segment dysgenesis autism spectrum disorder autosomal recessive polycystic kidney disease spinal disease tuberous sclerosis	ENSMUSG00000026812 (Ensembl Gene Model) ENSMUSP00000109500 (Ensembl) ENSMUST00000113869 (Ensembl)
rat	Tsc1	RGD:620124 (Rat Genome Database) 60445 (Entrez Gene) Tsc1 (Alliance of Genome Resources)	Chr3 p12			Q9Z136 (UniProt | EBI) NM_021854 (RefSeq)
zebrafish	tsc1a	ZDB-GENE-030131-9111 (Zebrafish Model Organism Database) 337167 (Entrez Gene) tsc1a (Alliance of Genome Resources)	Chr5			NP_956346 (RefSeq) NM_200052 (RefSeq)
	tsc1b	ZDB-GENE-030131-3404 (Zebrafish Model Organism Database) 100330617 (Entrez Gene) tsc1b (Alliance of Genome Resources)	Chr21			NP_001269321 (RefSeq) NM_001282392 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.