Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HMGB1	HGNC:4983 (HGNC) 3146 (Entrez Gene) 163905 (OMIM) HMGB1 (Alliance of Genome Resources)	Chr13 q12.3	Chr13:30456704-30617597 (-) GRCh38	amyotrophic lateral sclerosis	P09429 (UniProt | EBI) NM_002128 (RefSeq)
mouse	Hmgb1	MGI:96113 (MGI) 15289 (Entrez Gene) Gene Tree Hmgb1 (Alliance of Genome Resources)	Chr5 89.18 cM	Chr5:148983512-148989867 (-) GRCm39		15289 (NCBI Gene Model) P63158 (UniProt | EBI) NM_001313894 (RefSeq)
rat	Hmgb1	RGD:2802 (Rat Genome Database) 25459 (Entrez Gene) Hmgb1 (Alliance of Genome Resources)	Chr12 p11			P63159 (UniProt | EBI) NM_012963 (RefSeq)
	Hmgb1l2	RGD:11468204 (Rat Genome Database) 108349189 (Entrez Gene) Hmgb1l2 (Alliance of Genome Resources)	ChrX			XP_038956208 (RefSeq)
zebrafish	hmgb1a	ZDB-GENE-030131-341 (Zebrafish Model Organism Database) 321622 (Entrez Gene) hmgb1a (Alliance of Genome Resources)	Chr10			NP_955849 (RefSeq) NM_199555 (RefSeq)
	hmgb1b	ZDB-GENE-030131-8480 (Zebrafish Model Organism Database) 795095 (Entrez Gene) hmgb1b (Alliance of Genome Resources)	Chr15			NP_001092721 (RefSeq) NM_001099251 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.