Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PARP1	HGNC:270 (HGNC) 142 (Entrez Gene) 173870 (OMIM) PARP1 (Alliance of Genome Resources)	Chr1 q42.12	Chr1:226360210-226408154 (-) GRCh38	Alzheimer's disease arthritis asthma autoimmune disease bacterial meningitis nephritis Parkinson's disease stomach carcinoma	P09874 (UniProt | EBI) NM_001618 (RefSeq)
mouse	Parp1	MGI:1340806 (MGI) 11545 (Entrez Gene) Gene Tree Parp1 (Alliance of Genome Resources)	Chr1 84.44 cM	Chr1:180396456-180428564 (+) GRCm39		11545 (NCBI Gene Model) P11103 (UniProt | EBI) NM_007415 (RefSeq)
rat	Parp1	RGD:2053 (Rat Genome Database) 25591 (Entrez Gene) Parp1 (Alliance of Genome Resources)	Chr13 q26			P27008 (UniProt | EBI) NM_013063 (RefSeq)
zebrafish	parp1	ZDB-GENE-030131-3955 (Zebrafish Model Organism Database) 560788 (Entrez Gene) parp1 (Alliance of Genome Resources)	Chr20			Q5RHR0 (UniProt | EBI) NM_001044942 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.