Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CALR	HGNC:1455 (HGNC) 811 (Entrez Gene) 109091 (OMIM) CALR (Alliance of Genome Resources)	Chr19 p13.13	Chr19:12938578-12944489 (+) GRCh38	Burkitt lymphoma colon cancer colon carcinoma esophagus squamous cell carcinoma essential thrombocythemia hepatocellular carcinoma lung adenocarcinoma lung cancer myelofibrosis neuroendocrine tumor pancreatic ductal adenocarcinoma sideroblastic anemia thrombocytosis	P27797 (UniProt | EBI) NM_004343 (RefSeq)
mouse	Calr	MGI:88252 (MGI) 12317 (Entrez Gene) Gene Tree Calr (Alliance of Genome Resources)	Chr8 41.21 cM	Chr8:85568717-85573560 (-) GRCm39	congestive heart failure	12317 (NCBI Gene Model) P14211 (UniProt | EBI) NM_007591 (RefSeq)
rat	Calr	RGD:620288 (Rat Genome Database) 64202 (Entrez Gene) Calr (Alliance of Genome Resources)	Chr19 q11			P18418 (UniProt | EBI) NM_022399 (RefSeq)
zebrafish	calr	ZDB-GENE-030131-4042 (Zebrafish Model Organism Database) 325317 (Entrez Gene) calr (Alliance of Genome Resources)	Chr8			NP_956007 (RefSeq) NM_199713 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.