Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IRF2	HGNC:6117 (HGNC) 3660 (Entrez Gene) 147576 (OMIM) IRF2 (Alliance of Genome Resources)	Chr4 q35.1	Chr4:184385702-184474558 (-) GRCh38		P14316 (UniProt | EBI) NM_002199 (RefSeq)
mouse	Irf2	MGI:96591 (MGI) 16363 (Entrez Gene) Gene Tree Irf2 (Alliance of Genome Resources)	Chr8 26.42 cM	Chr8:47192767-47300493 (+) GRCm39		ENSMUSG00000031627 (Ensembl Gene Model) ENSMUSP00000034041 (Ensembl) ENSMUST00000034041 (Ensembl)
rat	Irf2	RGD:1304922 (Rat Genome Database) 290749 (Entrez Gene) Irf2 (Alliance of Genome Resources)	Chr16 q11			NP_001040551 (RefSeq) NM_001047086 (RefSeq)
zebrafish	irf2a	ZDB-GENE-030131-4135 (Zebrafish Model Organism Database) 325410 (Entrez Gene) irf2a (Alliance of Genome Resources)	Chr1			NP_996937 (RefSeq) NM_001326712 (RefSeq)
	irf2b	ZDB-GENE-041212-38 (Zebrafish Model Organism Database) 494071 (Entrez Gene) irf2b (Alliance of Genome Resources)	Chr14			NP_001315303 (RefSeq) NM_001008614 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.