Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SYNE1	HGNC:17089 (HGNC) 23345 (Entrez Gene) 608441 (OMIM) SYNE1 (Alliance of Genome Resources)	Chr6 q25.2	Chr6:152121687-152637801 (-) GRCh38	arthrogryposis multiplex congenita arthrogryposis multiplex congenita-3 autosomal dominant Emery-Dreifuss muscular dystrophy 4 autosomal recessive spinocerebellar ataxia 8 bipolar disorder cerebellar ataxia muscular dystrophy	Q8NF91 (UniProt | EBI) NM_182961 (RefSeq)
mouse	Syne1	MGI:1927152 (MGI) 64009 (Entrez Gene) Gene Tree Syne1 (Alliance of Genome Resources)	Chr10 2.01 cM	Chr10:4970917-5501482 (-) GRCm39	Emery-Dreifuss muscular dystrophy	ENSMUSG00000096054 (Ensembl Gene Model) ENSMUSP00000150262 (Ensembl) ENSMUST00000215295 (Ensembl)
zebrafish	syne1a	ZDB-GENE-030131-4172 (Zebrafish Model Organism Database) 569553 (Entrez Gene) syne1a (Alliance of Genome Resources)	Chr20			XP_021329047 (RefSeq)
	syne1b	ZDB-GENE-071218-4 (Zebrafish Model Organism Database) 567576 (Entrez Gene) syne1b (Alliance of Genome Resources)	Chr17			XP_017207244 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.