Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EPAS1	HGNC:3374 (HGNC) 2034 (Entrez Gene) 603349 (OMIM) EPAS1 (Alliance of Genome Resources)	Chr2 p21	Chr2:46293667-46386697 (+) GRCh38	familial erythrocytosis 4 lung non-small cell carcinoma polycythemia pulmonary hypertension	Q99814 (UniProt | EBI) NM_001430 (RefSeq)
mouse	Epas1	MGI:109169 (MGI) 13819 (Entrez Gene) Gene Tree Epas1 (Alliance of Genome Resources)	Chr17 56.9 cM	Chr17:87061292-87140838 (+) GRCm39	newborn respiratory distress syndrome	13819 (NCBI Gene Model) P97481 (UniProt | EBI) NM_010137 (RefSeq)
rat	Epas1	RGD:68404 (Rat Genome Database) 29452 (Entrez Gene) Epas1 (Alliance of Genome Resources)	Chr6 q12			Q9JHS1 (UniProt | EBI) NM_023090 (RefSeq)
zebrafish	epas1a	ZDB-GENE-030131-4490 (Zebrafish Model Organism Database) 566886 (Entrez Gene) epas1a (Alliance of Genome Resources)	Chr12			XP_009305016 (RefSeq)
	epas1b	ZDB-GENE-060607-11 (Zebrafish Model Organism Database) 555192 (Entrez Gene) epas1b (Alliance of Genome Resources)	Chr13			NP_001034895 (RefSeq) NM_001039806 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.