Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WRAP53	HGNC:25522 (HGNC) 55135 (Entrez Gene) 612661 (OMIM) WRAP53 (Alliance of Genome Resources)	Chr17 p13.1	Chr17:7686071-7703502 (+) GRCh38	autosomal recessive dyskeratosis congenita 3 colorectal cancer head and neck squamous cell carcinoma lung non-small cell carcinoma ovarian cancer	Q9BUR4 (UniProt | EBI) NM_001143992 (RefSeq)
mouse	Wrap53	MGI:2384933 (MGI) 216853 (Entrez Gene) Gene Tree Wrap53 (Alliance of Genome Resources)	Chr11 42.81 cM	Chr11:69452580-69471076 (-) GRCm39		216853 (NCBI Gene Model) Q8VC51 (UniProt | EBI) NM_001364769 (RefSeq)
rat	Wrap53	RGD:1359624 (Rat Genome Database) 287432 (Entrez Gene) Wrap53 (Alliance of Genome Resources)	Chr10 q24			Q5XII5 (UniProt | EBI) NM_001007610 (RefSeq)
zebrafish	wrap53	ZDB-GENE-030131-515 (Zebrafish Model Organism Database) 321796 (Entrez Gene) wrap53 (Alliance of Genome Resources)	Chr7			NP_001242957 (RefSeq) NM_001256028 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.