Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	POLR1A	HGNC:17264 (HGNC) 25885 (Entrez Gene) 616404 (OMIM) POLR1A (Alliance of Genome Resources)	Chr2 p11.2	Chr2:86020216-86106155 (-) GRCh38	acrofacial dysostosis Cincinnati type hypomyelinating leukodystrophy	O95602 (UniProt | EBI) NM_015425 (RefSeq)
mouse	Polr1a	MGI:1096397 (MGI) 20019 (Entrez Gene) Gene Tree Polr1a (Alliance of Genome Resources)	Chr6 32.21 cM	Chr6:71886037-71956419 (+) GRCm39		20019 (NCBI Gene Model) O35134 (UniProt | EBI) NM_009088 (RefSeq)
rat	Polr1a	RGD:620824 (Rat Genome Database) 83581 (Entrez Gene) Polr1a (Alliance of Genome Resources)	Chr4 q32			O54889 (UniProt | EBI) NM_031772 (RefSeq)
zebrafish	polr1a	ZDB-GENE-030131-5286 (Zebrafish Model Organism Database) 327078 (Entrez Gene) polr1a (Alliance of Genome Resources)	Chr14			XP_001922839 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.