Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2B5	HGNC:3261 (HGNC) 8893 (Entrez Gene) 603945 (OMIM) EIF2B5 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:184135038-184146127 (+) GRCh38	leukoencephalopathy with vanishing white matter leukoencephalopathy with vanishing white matter 5	Q13144 (UniProt | EBI) NM_003907 (RefSeq)
mouse	Eif2b5	MGI:2446176 (MGI) 224045 (Entrez Gene) Gene Tree Eif2b5 (Alliance of Genome Resources)	Chr16 12.45 cM	Chr16:20317567-20328073 (+) GRCm39	leukoencephalopathy with vanishing white matter	ENSMUSG00000003235 (Ensembl Gene Model) ENSMUSP00000003320 (Ensembl) ENSMUST00000003320 (Ensembl)
rat	Eif2b5	RGD:708380 (Rat Genome Database) 192234 (Entrez Gene) Eif2b5 (Alliance of Genome Resources)	Chr11 q23			Q64350 (UniProt | EBI) NM_138866 (RefSeq)
zebrafish	eif2b5	ZDB-GENE-030131-5364 (Zebrafish Model Organism Database) 563613 (Entrez Gene) eif2b5 (Alliance of Genome Resources)	Chr2			NP_001107069 (RefSeq) NM_001113597 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.