Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RAC1	HGNC:9801 (HGNC) 5879 (Entrez Gene) 602048 (OMIM) RAC1 (Alliance of Genome Resources)	Chr7 p22.1	Chr7:6374527-6403967 (+) GRCh38	autosomal dominant intellectual developmental disorder 48 colon adenocarcinoma colorectal cancer colorectal carcinoma lung cancer pancreatic adenocarcinoma	P63000 (UniProt | EBI) NM_018890 (RefSeq)
mouse	Rac1	MGI:97845 (MGI) 19353 (Entrez Gene) Gene Tree Rac1 (Alliance of Genome Resources)	Chr5 82.22 cM	Chr5:143491236-143513786 (-) GRCm39		19353 (NCBI Gene Model) P63001 (UniProt | EBI) NM_001347530 (RefSeq)
rat	Rac1	RGD:619755 (Rat Genome Database) 363875 (Entrez Gene) Rac1 (Alliance of Genome Resources)	Chr12 p11			Q6RUV5 (UniProt | EBI) NM_134366 (RefSeq)
zebrafish	rac1a	ZDB-GENE-030131-5415 (Zebrafish Model Organism Database) 327204 (Entrez Gene) rac1a (Alliance of Genome Resources)	Chr12			NP_956065 (RefSeq) NM_199771 (RefSeq)
	rac1b	ZDB-GENE-060312-45 (Zebrafish Model Organism Database) 562838 (Entrez Gene) rac1b (Alliance of Genome Resources)	Chr3			NP_001034907 (RefSeq) NM_001039818 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.