Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2S3	HGNC:3267 (HGNC) 1968 (Entrez Gene) 300161 (OMIM) EIF2S3 (Alliance of Genome Resources)	ChrX p22.11	ChrX:24054946-24078810 (+) GRCh38	MEHMO syndrome	P41091 (UniProt | EBI) NM_001415 (RefSeq)
	EIF2S3B	HGNC:43863 (HGNC) 255308 (Entrez Gene) EIF2S3B (Alliance of Genome Resources)	Chr12 p13.2	Chr12:10505602-10523135 (+) GRCh38		Q2VIR3 (UniProt | EBI) NM_001357734 (RefSeq)
mouse	Eif2s3x	MGI:1349431 (MGI) 26905 (Entrez Gene) Gene Tree Eif2s3x (Alliance of Genome Resources)	ChrX 41.52 cM	ChrX:93232315-93256257 (-) GRCm39		26905 (NCBI Gene Model) Q9Z0N1 (UniProt | EBI) NM_012010 (RefSeq)
rat	Eif2s3	RGD:1561279 (Rat Genome Database) 299027 (Entrez Gene) Eif2s3 (Alliance of Genome Resources)	ChrX q22			P81795 (UniProt | EBI) NM_001100542 (RefSeq)
zebrafish	eif2s3	ZDB-GENE-030131-5552 (Zebrafish Model Organism Database) 327341 (Entrez Gene) eif2s3 (Alliance of Genome Resources)	Chr24			F1QGW6 (UniProt | EBI) NM_212711 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.