Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PFKFB1	HGNC:8872 (HGNC) 5207 (Entrez Gene) 311790 (OMIM) PFKFB1 (Alliance of Genome Resources)	ChrX p11.21	ChrX:54932961-54998789 (-) GRCh38		P16118 (UniProt | EBI) NM_002625 (RefSeq)
mouse	Pfkfb1	MGI:107816 (MGI) 18639 (Entrez Gene) Gene Tree Pfkfb1 (Alliance of Genome Resources)	ChrX 68.46 cM	ChrX:149371225-149426874 (+) GRCm39		ENSMUSG00000025271 (Ensembl Gene Model) ENSMUSP00000108333 (Ensembl) ENSMUST00000112713 (Ensembl)
rat	Pfkfb1	RGD:3307 (Rat Genome Database) 24638 (Entrez Gene) Pfkfb1 (Alliance of Genome Resources)	ChrX q12			P07953 (UniProt | EBI) NM_012621 (RefSeq)
zebrafish	pfkfb1	ZDB-GENE-030131-5664 (Zebrafish Model Organism Database) 327453 (Entrez Gene) pfkfb1 (Alliance of Genome Resources)	Chr23			NP_956102 (RefSeq) NM_199808 (RefSeq)
	si:dkey-96f10.1	ZDB-GENE-090312-154 (Zebrafish Model Organism Database) 100330415 (Entrez Gene) si:dkey-96f10.1 (Alliance of Genome Resources)	Chr23			XP_002666487 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.