Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSD11B2	HGNC:5209 (HGNC) 3291 (Entrez Gene) 614232 (OMIM) HSD11B2 (Alliance of Genome Resources)	Chr16 q22.1	Chr16:67429801-67437553 (+) GRCh38	apparent mineralocorticoid excess syndrome hypertension inherited metabolic disorder obesity type 1 diabetes mellitus	P80365 (UniProt | EBI) NM_000196 (RefSeq)
mouse	Hsd11b2	MGI:104720 (MGI) 15484 (Entrez Gene) Gene Tree Hsd11b2 (Alliance of Genome Resources)	Chr8 53.04 cM	Chr8:106245387-106250620 (+) GRCm39		ENSMUSG00000031891 (Ensembl Gene Model) ENSMUSP00000034363 (Ensembl) ENSMUST00000034363 (Ensembl)
rat	Hsd11b2	RGD:2835 (Rat Genome Database) 25117 (Entrez Gene) Hsd11b2 (Alliance of Genome Resources)	Chr19 q12			P50233 (UniProt | EBI) NM_017081 (RefSeq)
zebrafish	hsd11b2	ZDB-GENE-030131-6030 (Zebrafish Model Organism Database) 334098 (Entrez Gene) hsd11b2 (Alliance of Genome Resources)	Chr7			F1QLP1 (UniProt | EBI) NM_212720 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.