Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHD8	HGNC:20153 (HGNC) 57680 (Entrez Gene) 610528 (OMIM) CHD8 (Alliance of Genome Resources)	Chr14 q11.2	Chr14:21385194-21456126 (-) GRCh38		Q9HCK8 (UniProt | EBI) NM_020920 (RefSeq)
mouse	Chd8	MGI:1915022 (MGI) 67772 (Entrez Gene) Gene Tree Chd8 (Alliance of Genome Resources)	Chr14 26.84 cM	Chr14:52435608-52495237 (-) GRCm39	autism spectrum disorder	ENSMUSG00000053754 (Ensembl Gene Model) ENSMUSP00000087184 (Ensembl) ENSMUST00000089752 (Ensembl)
rat	Chd8	RGD:620696 (Rat Genome Database) 65027 (Entrez Gene) Chd8 (Alliance of Genome Resources)	Chr15 p14			Q9JIX5 (UniProt | EBI) NM_001347661 (RefSeq)
zebrafish	chd8	ZDB-GENE-030131-6320 (Zebrafish Model Organism Database) 568214 (Entrez Gene) chd8 (Alliance of Genome Resources)	Chr2			B0R0I6 (UniProt | EBI) NM_001347671 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.