Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TOPORS	HGNC:21653 (HGNC) 10210 (Entrez Gene) 609507 (OMIM) TOPORS (Alliance of Genome Resources)	Chr9 p21.1	Chr9:32540544-32552586 (-) GRCh38	retinitis pigmentosa 31	Q9NS56 (UniProt | EBI) NM_005802 (RefSeq)
mouse	Topors	MGI:2146189 (MGI) 106021 (Entrez Gene) Gene Tree Topors (Alliance of Genome Resources)	Chr4 20.24 cM	Chr4:40259606-40269841 (-) GRCm39		106021 (NCBI Gene Model) Q80Z37 (UniProt | EBI) NM_134097 (RefSeq)
rat	Topors	RGD:1305270 (Rat Genome Database) 362501 (Entrez Gene) Topors (Alliance of Genome Resources)	Chr5 q22			NP_001102128 (RefSeq) NM_001108658 (RefSeq)
zebrafish	toporsa	ZDB-GENE-030131-6401 (Zebrafish Model Organism Database) 324197 (Entrez Gene) toporsa (Alliance of Genome Resources)	Chr1			NP_001292484 (RefSeq) NM_001305555 (RefSeq)
	toporsb	ZDB-GENE-110728-3 (Zebrafish Model Organism Database) 796087 (Entrez Gene) toporsb (Alliance of Genome Resources)	ChrUN			XP_003201680 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.