Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TPP1	HGNC:2073 (HGNC) 1200 (Entrez Gene) 607998 (OMIM) TPP1 (Alliance of Genome Resources)	Chr11 p15.4	Chr11:6612768-6619448 (-) GRCh38	autosomal recessive spinocerebellar ataxia 7 neuronal ceroid lipofuscinosis 2	O14773 (UniProt | EBI) NM_000391 (RefSeq)
mouse	Tpp1	MGI:1336194 (MGI) 12751 (Entrez Gene) Gene Tree Tpp1 (Alliance of Genome Resources)	Chr7 55.97 cM	Chr7:105394018-105401442 (-) GRCm39	neuronal ceroid lipofuscinosis 2	ENSMUSG00000030894 (Ensembl Gene Model) ENSMUSP00000033184 (Ensembl) ENSMUST00000033184 (Ensembl)
rat	Tpp1	RGD:621296 (Rat Genome Database) 83534 (Entrez Gene) Tpp1 (Alliance of Genome Resources)	Chr1 q32			Q9EQV6 (UniProt | EBI) NM_031357 (RefSeq)
zebrafish	tpp1	ZDB-GENE-030131-6654 (Zebrafish Model Organism Database) 798347 (Entrez Gene) tpp1 (Alliance of Genome Resources)	Chr17			F8W2M8 (UniProt | EBI) NM_001128798 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.