Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	COL10A1	HGNC:2185 (HGNC) 1300 (Entrez Gene) 120110 (OMIM) COL10A1 (Alliance of Genome Resources)	Chr6 q22.1	Chr6:116118909-116217144 (-) GRCh38	osteochondrodysplasia Schmid metaphyseal chondrodysplasia	Q03692 (UniProt | EBI) NM_001424107 (RefSeq)
mouse	Col10a1	MGI:88445 (MGI) 12813 (Entrez Gene) Gene Tree Col10a1 (Alliance of Genome Resources)	Chr10 18.85 cM	Chr10:34265977-34273081 (+) GRCm39	Schmid metaphyseal chondrodysplasia	12813 (NCBI Gene Model) Q05306 (UniProt | EBI) NM_009925 (RefSeq)
rat	Col10a1	RGD:2371 (Rat Genome Database) 25681 (Entrez Gene) Col10a1 (Alliance of Genome Resources)	Chr20 q12			NP_037272 (RefSeq) NM_013140 (RefSeq)
zebrafish	col10a1a	ZDB-GENE-030131-8373 (Zebrafish Model Organism Database) 558919 (Entrez Gene) col10a1a (Alliance of Genome Resources)	Chr17			NP_001077296 (RefSeq) NM_001083827 (RefSeq)
	col10a1b	ZDB-GENE-030131-7079 (Zebrafish Model Organism Database) 555804 (Entrez Gene) col10a1b (Alliance of Genome Resources)	Chr20			XP_683515 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.