PON1 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PON1	HGNC:9204 (HGNC) 5444 (Entrez Gene) 168820 (OMIM) PON1 (Alliance of Genome Resources)	Chr7 q21.3	Chr7:95297676-95324532 (-) GRCh38	abdominal aortic aneurysm acute lymphoblastic leukemia Alzheimer's disease anemia arteriosclerosis atherosclerosis breast cancer capillary leak syndrome cerebral cavernous malformation cerebral infarction chronic lymphocytic leukemia coronary artery disease dementia diabetic angiopathy diabetic retinopathy glucose intolerance Henoch-Schoenlein purpura hyperglycemia hypertension iron deficiency anemia Kuhnt-Junius degeneration macular degeneration multiple myeloma myocardial infarction non-Hodgkin lymphoma open-angle glaucoma primary open angle glaucoma retinal vein occlusion type 2 diabetes mellitus	P27169 (UniProt \| EBI) NM_000446 (RefSeq)
mouse	Pon1	MGI:103295 (MGI) 18979 (Entrez Gene) Gene Tree Pon1 (Alliance of Genome Resources)	Chr6 1.99 cM	Chr6:5168101-5193824 (-) GRCm39		18979 (NCBI Gene Model) P52430 (UniProt \| EBI) NM_001410259 (RefSeq)
rat	Pon1	RGD:620062 (Rat Genome Database) 84024 (Entrez Gene) Pon1 (Alliance of Genome Resources)	Chr4 q21			P55159 (UniProt \| EBI) NM_032077 (RefSeq)
zebrafish	pon1	ZDB-GENE-040912-6 (Zebrafish Model Organism Database) 447803 (Entrez Gene) pon1 (Alliance of Genome Resources)	Chr16			NP_001004542 (RefSeq) NM_001004542 (RefSeq)
	pon2	ZDB-GENE-030131-7116 (Zebrafish Model Organism Database) 335176 (Entrez Gene) pon2 (Alliance of Genome Resources)	Chr16			NP_997899 (RefSeq) NM_212734 (RefSeq)
	pon3.1	ZDB-GENE-050522-353 (Zebrafish Model Organism Database) 554122 (Entrez Gene) pon3.1 (Alliance of Genome Resources)	Chr16			NP_001019588 (RefSeq) NM_001024417 (RefSeq)
	pon3.2	ZDB-GENE-071004-70 (Zebrafish Model Organism Database) 568655 (Entrez Gene) pon3.2 (Alliance of Genome Resources)	Chr16			NP_001098592 (RefSeq) NM_001105122 (RefSeq)