Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MECP2	HGNC:6990 (HGNC) 4204 (Entrez Gene) 300005 (OMIM) MECP2 (Alliance of Genome Resources)	ChrX q28	ChrX:154021573-154137103 (-) GRCh38	autistic disorder gastrointestinal system disease Rett syndrome severe congenital encephalopathy due to MECP2 mutation syndromic X-linked intellectual disability Lubs type X-linked intellectual disability-psychosis-macroorchidism syndrome	P51608 (UniProt | EBI) NM_001369394 (RefSeq)
mouse	Mecp2	MGI:99918 (MGI) 17257 (Entrez Gene) Gene Tree Mecp2 (Alliance of Genome Resources)	ChrX 37.63 cM	ChrX:73070198-73129296 (-) GRCm39	Rett syndrome	17257 (NCBI Gene Model) Q9Z2D6 (UniProt | EBI) NM_010788 (RefSeq)
rat	Mecp2	RGD:3075 (Rat Genome Database) 29386 (Entrez Gene) Mecp2 (Alliance of Genome Resources)	ChrX			Q00566 (UniProt | EBI) NM_022673 (RefSeq)
zebrafish	mecp2	ZDB-GENE-030131-7190 (Zebrafish Model Organism Database) 335250 (Entrez Gene) mecp2 (Alliance of Genome Resources)	Chr8			NP_001315484 (RefSeq) NM_212736 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.