Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GSDME	HGNC:2810 (HGNC) 1687 (Entrez Gene) 608798 (OMIM) GSDME (Alliance of Genome Resources)	Chr7 p15.3	Chr7:24698355-24795539 (-) GRCh38	autosomal dominant nonsyndromic deafness 5 sensorineural hearing loss	O60443 (UniProt | EBI) NM_001127453 (RefSeq)
mouse	Gsdme	MGI:1889850 (MGI) 54722 (Entrez Gene) Gene Tree Gsdme (Alliance of Genome Resources)	Chr6 24.13 cM	Chr6:50167013-50240837 (-) GRCm39		54722 (NCBI Gene Model) Q9Z2D3 (UniProt | EBI) NM_018769 (RefSeq)
rat	Gsdme	RGD:727871 (Rat Genome Database) 353316 (Entrez Gene) Gsdme (Alliance of Genome Resources)	Chr4 q24			NP_001178678 (RefSeq) NM_001191749 (RefSeq)
zebrafish	gsdmea	ZDB-GENE-120215-186 (Zebrafish Model Organism Database) 101884911 (Entrez Gene) gsdmea (Alliance of Genome Resources)	Chr19			XP_005170134 (RefSeq)
	gsdmeb	ZDB-GENE-030131-7662 (Zebrafish Model Organism Database) 335722 (Entrez Gene) gsdmeb (Alliance of Genome Resources)	Chr16			NP_001001947 (RefSeq) NM_001001947 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.