Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MMP2	HGNC:7166 (HGNC) 4313 (Entrez Gene) 120360 (OMIM) MMP2 (Alliance of Genome Resources)	Chr16 q12.2	Chr16:55389700-55506691 (+) GRCh38	arteriosclerosis carotid artery disease diabetic retinopathy hypertension intracranial aneurysm macular degeneration myopia pseudoxanthoma elasticum pterygium retinal vein occlusion temporal arteritis	P08253 (UniProt | EBI) NM_001127891 (RefSeq)
mouse	Mmp2	MGI:97009 (MGI) 17390 (Entrez Gene) Gene Tree Mmp2 (Alliance of Genome Resources)	Chr8 44.99 cM	Chr8:93553920-93580049 (+) GRCm39		17390 (NCBI Gene Model) P33434 (UniProt | EBI) NM_008610 (RefSeq)
rat	Mmp2	RGD:621316 (Rat Genome Database) 81686 (Entrez Gene) Mmp2 (Alliance of Genome Resources)	Chr19 p11			P33436 (UniProt | EBI) NM_031054 (RefSeq)
zebrafish	mmp2	ZDB-GENE-030131-9123 (Zebrafish Model Organism Database) 337179 (Entrez Gene) mmp2 (Alliance of Genome Resources)	Chr7			NP_932333 (RefSeq) NM_198067 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.