Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALOX5AP	HGNC:436 (HGNC) 241 (Entrez Gene) 603700 (OMIM) ALOX5AP (Alliance of Genome Resources)	Chr13 q12.3	Chr13:30713478-30764426 (+) GRCh38	asthma brain infarction breast cancer cerebral infarction cerebral palsy coronary artery disease kidney disease myocardial infarction	P20292 (UniProt | EBI) NM_001629 (RefSeq)
mouse	Alox5ap	MGI:107505 (MGI) 11690 (Entrez Gene) Gene Tree Alox5ap (Alliance of Genome Resources)	Chr5 89.18 cM	Chr5:149201814-149224963 (+) GRCm39		11690 (NCBI Gene Model) P30355 (UniProt | EBI) NM_009663 (RefSeq)
rat	Alox5ap	RGD:2097 (Rat Genome Database) 29624 (Entrez Gene) Alox5ap (Alliance of Genome Resources)	Chr12 p11			P20291 (UniProt | EBI) NM_017260 (RefSeq)
zebrafish	alox5ap	ZDB-GENE-030131-9322 (Zebrafish Model Organism Database) 337376 (Entrez Gene) alox5ap (Alliance of Genome Resources)	Chr10			NP_956355 (RefSeq) NM_200061 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.