Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PAICS	HGNC:8587 (HGNC) 10606 (Entrez Gene) 172439 (OMIM) PAICS (Alliance of Genome Resources)	Chr4 q12	Chr4:56410507-56464578 (+) GRCh38	schizophrenia	P22234 (UniProt | EBI) NM_006452 (RefSeq)
mouse	Paics	MGI:1914304 (MGI) 67054 (Entrez Gene) Gene Tree Paics (Alliance of Genome Resources)	Chr5 41.45 cM	Chr5:77099154-77115356 (+) GRCm39		ENSMUSG00000029247 (Ensembl Gene Model) ENSMUSP00000031160 (Ensembl) ENSMUST00000031160 (Ensembl)
rat	LOC100359876	RGD:2323267 (Rat Genome Database) 100359876 (Entrez Gene) LOC100359876 (Alliance of Genome Resources)	ChrX			XP_038956166 (RefSeq)
	Paics	RGD:620066 (Rat Genome Database) 140946 (Entrez Gene) Paics (Alliance of Genome Resources)	Chr14 p11			P51583 (UniProt | EBI) NM_080910 (RefSeq)
zebrafish	paics	ZDB-GENE-030131-9762 (Zebrafish Model Organism Database) 321193 (Entrez Gene) paics (Alliance of Genome Resources)	Chr20			NP_955831 (RefSeq) NM_199537 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.