Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PMEL	HGNC:10880 (HGNC) 6490 (Entrez Gene) 155550 (OMIM) PMEL (Alliance of Genome Resources)	Chr12 q13.2	Chr12:55954105-55973317 (-) GRCh38		P40967 (UniProt | EBI) NM_001200053 (RefSeq)
mouse	Pmel	MGI:98301 (MGI) 20431 (Entrez Gene) Gene Tree Pmel (Alliance of Genome Resources)	Chr10 77.13 cM	Chr10:128540064-128556107 (+) GRCm39		ENSMUSG00000025359 (Ensembl Gene Model) ENSMUSP00000051869 (Ensembl) ENSMUST00000054125 (Ensembl)
rat	Pmel	RGD:1307513 (Rat Genome Database) 362818 (Entrez Gene) Pmel (Alliance of Genome Resources)	Chr7 q11			NP_001414117 (RefSeq) NM_001427188 (RefSeq)
zebrafish	pmela	ZDB-GENE-030131-9818 (Zebrafish Model Organism Database) 321239 (Entrez Gene) pmela (Alliance of Genome Resources)	Chr11			NP_001038795 (RefSeq) NM_001045330 (RefSeq)
	pmelb	ZDB-GENE-050912-2 (Zebrafish Model Organism Database) 562810 (Entrez Gene) pmelb (Alliance of Genome Resources)	Chr23			NP_001029090 (RefSeq) NM_001033918 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.