Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EFEMP2	HGNC:3219 (HGNC) 30008 (Entrez Gene) 604633 (OMIM) EFEMP2 (Alliance of Genome Resources)	Chr11 q13.1	Chr11:65866441-65873592 (-) GRCh38	aortic aneurysm arterial tortuosity syndrome autosomal recessive cutis laxa type IB endometrial cancer osteosarcoma	O95967 (UniProt | EBI) NM_016938 (RefSeq)
mouse	Efemp2	MGI:1891209 (MGI) 58859 (Entrez Gene) Gene Tree Efemp2 (Alliance of Genome Resources)	Chr19 4.33 cM	Chr19:5523982-5532545 (+) GRCm39	aortic aneurysm cutis laxa	ENSMUSG00000024909 (Ensembl Gene Model) ENSMUSP00000064719 (Ensembl) ENSMUST00000070118 (Ensembl)
rat	Efemp2	RGD:1359496 (Rat Genome Database) 293677 (Entrez Gene) Efemp2 (Alliance of Genome Resources)	Chr1 q43			NP_001264270 (RefSeq) NM_001005907 (RefSeq)
zebrafish	efemp2a	ZDB-GENE-041212-8 (Zebrafish Model Organism Database) 494044 (Entrez Gene) efemp2a (Alliance of Genome Resources)	Chr14			NP_001008587 (RefSeq) NM_001008587 (RefSeq)
	efemp2b	ZDB-GENE-030219-125 (Zebrafish Model Organism Database) 572703 (Entrez Gene) efemp2b (Alliance of Genome Resources)	Chr21			NP_001153830 (RefSeq) NM_001160358 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.