Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IMPDH1	HGNC:6052 (HGNC) 3614 (Entrez Gene) 146690 (OMIM) IMPDH1 (Alliance of Genome Resources)	Chr7 q32.1	Chr7:128392277-128409986 (-) GRCh38	Leber congenital amaurosis 11 retinitis pigmentosa retinitis pigmentosa 10	P20839 (UniProt | EBI) NM_001102605 (RefSeq)
mouse	Impdh1	MGI:96567 (MGI) 23917 (Entrez Gene) Gene Tree Impdh1 (Alliance of Genome Resources)	Chr6 12.36 cM	Chr6:29200435-29216363 (-) GRCm39		23917 (NCBI Gene Model) P50096 (UniProt | EBI) NM_001302933 (RefSeq)
rat	Impdh1	RGD:1311108 (Rat Genome Database) 362329 (Entrez Gene) Impdh1 (Alliance of Genome Resources)	Chr4 q22			D3ZLZ7 (UniProt | EBI) NM_001398857 (RefSeq)
zebrafish	impdh1a	ZDB-GENE-040704-15 (Zebrafish Model Organism Database) 431724 (Entrez Gene) impdh1a (Alliance of Genome Resources)	Chr18			Q6GMG5 (UniProt | EBI) NM_001002177 (RefSeq)
	impdh1b	ZDB-GENE-030219-206 (Zebrafish Model Organism Database) 338306 (Entrez Gene) impdh1b (Alliance of Genome Resources)	Chr4			Q5RGV1 (UniProt | EBI) NM_001014369 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.