Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRM2	HGNC:1951 (HGNC) 1129 (Entrez Gene) 118493 (OMIM) CHRM2 (Alliance of Genome Resources)	Chr7 q33	Chr7:136868652-137020255 (+) GRCh38	asthma bipolar disorder Chagas disease heroin dependence major depressive disorder schizophrenia	P08172 (UniProt | EBI) NM_000739 (RefSeq)
mouse	Chrm2	MGI:88397 (MGI) 243764 (Entrez Gene) Gene Tree Chrm2 (Alliance of Genome Resources)	Chr6 15.48 cM	Chr6:36365019-36505349 (+) GRCm39		ENSMUSG00000045613 (Ensembl Gene Model) ENSMUSP00000130874 (Ensembl) ENSMUST00000172278 (Ensembl)
rat	Chrm2	RGD:620023 (Rat Genome Database) 81645 (Entrez Gene) Chrm2 (Alliance of Genome Resources)	Chr4 q22			P10980 (UniProt | EBI) NM_031016 (RefSeq)
zebrafish	chrm2a	ZDB-GENE-030314-1 (Zebrafish Model Organism Database) 352938 (Entrez Gene) chrm2a (Alliance of Genome Resources)	Chr4			NP_840086 (RefSeq) NM_178301 (RefSeq)
	chrm2b	ZDB-GENE-090410-3 (Zebrafish Model Organism Database) 555516 (Entrez Gene) chrm2b (Alliance of Genome Resources)	Chr25			XP_068073545 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.