Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CXCL12	HGNC:10672 (HGNC) 6387 (Entrez Gene) 600835 (OMIM) CXCL12 (Alliance of Genome Resources)	Chr10 q11.21	Chr10:44370165-44386493 (-) GRCh38	breast carcinoma diabetic angiopathy human immunodeficiency virus infectious disease type 1 diabetes mellitus	P48061 (UniProt | EBI) NM_001178134 (RefSeq)
mouse	Cxcl12	MGI:103556 (MGI) 20315 (Entrez Gene) Gene Tree Cxcl12 (Alliance of Genome Resources)	Chr6 54.81 cM	Chr6:117145496-117158328 (+) GRCm39		ENSMUSG00000061353 (Ensembl Gene Model) ENSMUSP00000072800 (Ensembl) ENSMUST00000073043 (Ensembl)
rat	Cxcl12	RGD:3651 (Rat Genome Database) 24772 (Entrez Gene) Cxcl12 (Alliance of Genome Resources)	Chr4 q42			NP_001029055 (RefSeq) NM_001033883 (RefSeq)
zebrafish	cxcl12a	ZDB-GENE-030318-1 (Zebrafish Model Organism Database) 352944 (Entrez Gene) cxcl12a (Alliance of Genome Resources)	Chr13			NP_840092 (RefSeq) NM_178307 (RefSeq)
	cxcl12b	ZDB-GENE-030721-1 (Zebrafish Model Organism Database) 799354 (Entrez Gene) cxcl12b (Alliance of Genome Resources)	Chr22			NP_001307343 (RefSeq) NM_001320414 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.