Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYO6	HGNC:7605 (HGNC) 4646 (Entrez Gene) 600970 (OMIM) MYO6 (Alliance of Genome Resources)	Chr6 q14.1	Chr6:75749201-75919537 (+) GRCh38	autosomal dominant nonsyndromic deafness 22 autosomal recessive nonsyndromic deafness 37 ovarian cancer sensorineural hearing loss	Q9UM54 (UniProt | EBI) NM_001368865 (RefSeq)
mouse	Myo6	MGI:104785 (MGI) 17920 (Entrez Gene) Gene Tree Myo6 (Alliance of Genome Resources)	Chr9 43.98 cM	Chr9:80072313-80219011 (+) GRCm39	autosomal dominant nonsyndromic deafness 22 autosomal recessive nonsyndromic deafness 37	ENSMUSG00000033577 (Ensembl Gene Model) ENSMUSP00000139019 (Ensembl) ENSMUST00000184480 (Ensembl)
rat	Myo6	RGD:1560646 (Rat Genome Database) 315840 (Entrez Gene) Myo6 (Alliance of Genome Resources)	Chr8 q31			NP_001414188 (RefSeq) NM_001427259 (RefSeq)
zebrafish	myo6a	ZDB-GENE-040819-2 (Zebrafish Model Organism Database) 445473 (Entrez Gene) myo6a (Alliance of Genome Resources)	Chr20			NP_001004111 (RefSeq) NM_001004111 (RefSeq)
	myo6b	ZDB-GENE-030318-3 (Zebrafish Model Organism Database) 445472 (Entrez Gene) myo6b (Alliance of Genome Resources)	Chr17			NP_001004110 (RefSeq) NM_001004110 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.