Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMARCA4	HGNC:11100 (HGNC) 6597 (Entrez Gene) 603254 (OMIM) SMARCA4 (Alliance of Genome Resources)	Chr19 p13.2	Chr19:10960932-11079426 (+) GRCh38	Coffin-Siris syndrome 4 hepatocellular carcinoma lung non-small cell carcinoma rhabdoid cancer	P51532 (UniProt | EBI) NM_001411150 (RefSeq)
mouse	Smarca4	MGI:88192 (MGI) 20586 (Entrez Gene) Gene Tree Smarca4 (Alliance of Genome Resources)	Chr9 7.84 cM	Chr9:21527465-21615526 (+) GRCm39	breast cancer	ENSMUSG00000032187 (Ensembl Gene Model) ENSMUSP00000096547 (Ensembl) ENSMUST00000098948 (Ensembl)
rat	Smarca4	RGD:621728 (Rat Genome Database) 171379 (Entrez Gene) Smarca4 (Alliance of Genome Resources)	Chr8 q13			Q8K1P7 (UniProt | EBI) NM_134368 (RefSeq)
zebrafish	smarca4a	ZDB-GENE-030605-1 (Zebrafish Model Organism Database) 353295 (Entrez Gene) smarca4a (Alliance of Genome Resources)	Chr3			NP_853634 (RefSeq) NM_181603 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.