Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ALK	HGNC:427 (HGNC) 238 (Entrez Gene) 105590 (OMIM) ALK (Alliance of Genome Resources)	Chr2 p23.2-p23.1	Chr2:29192774-29921586 (-) GRCh38		Q9UM73 (UniProt | EBI) NM_004304 (RefSeq)
mouse	Alk	MGI:103305 (MGI) 11682 (Entrez Gene) Gene Tree Alk (Alliance of Genome Resources)	Chr17 43.77 cM	Chr17:72175967-72911622 (-) GRCm39		ENSMUSG00000055471 (Ensembl Gene Model) ENSMUSP00000083840 (Ensembl) ENSMUST00000086639 (Ensembl)
rat	Alk	RGD:628622 (Rat Genome Database) 266802 (Entrez Gene) Alk (Alliance of Genome Resources)	Chr6 q14			NP_001162572 (RefSeq) NM_001169101 (RefSeq)
zebrafish	alk	ZDB-GENE-031027-1 (Zebrafish Model Organism Database) 563509 (Entrez Gene) alk (Alliance of Genome Resources)	Chr17			F8W3R9 (UniProt | EBI) NM_001423965 (RefSeq)
	ltk	ZDB-GENE-030616-115 (Zebrafish Model Organism Database) 564470 (Entrez Gene) ltk (Alliance of Genome Resources)	Chr17			F1QVU0 (UniProt | EBI) NM_001006660 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.