Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	STAT1	HGNC:11362 (HGNC) 6772 (Entrez Gene) 600555 (OMIM) STAT1 (Alliance of Genome Resources)	Chr2 q32.2	Chr2:190908460-191020960 (-) GRCh38	breast carcinoma colon adenocarcinoma immunodeficiency 31A immunodeficiency 31B immunodeficiency 31C prostate adenocarcinoma	P42224 (UniProt | EBI) NM_001384883 (RefSeq)
mouse	Stat1	MGI:103063 (MGI) 20846 (Entrez Gene) Gene Tree Stat1 (Alliance of Genome Resources)	Chr1 26.81 cM	Chr1:52158599-52201024 (+) GRCm39	breast cancer severe acute respiratory syndrome	ENSMUSG00000026104 (Ensembl Gene Model) ENSMUSP00000141132 (Ensembl) ENSMUST00000186057 (Ensembl)
rat	Stat1	RGD:3771 (Rat Genome Database) 25124 (Entrez Gene) Stat1 (Alliance of Genome Resources)	Chr9 q22			NP_116001 (RefSeq) NM_001034164 (RefSeq)
	Stat4	RGD:1305747 (Rat Genome Database) 367264 (Entrez Gene) Stat4 (Alliance of Genome Resources)	Chr9 q22			NP_001012226 (RefSeq) NM_001012226 (RefSeq)
zebrafish	stat1a	ZDB-GENE-980526-499 (Zebrafish Model Organism Database) 30768 (Entrez Gene) stat1a (Alliance of Genome Resources)	Chr22			NP_571555 (RefSeq) NM_131480 (RefSeq)
	stat1b	ZDB-GENE-030616-23 (Zebrafish Model Organism Database) 368481 (Entrez Gene) stat1b (Alliance of Genome Resources)	Chr9			NP_956385 (RefSeq) NM_200091 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.