Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TAP2	HGNC:44 (HGNC) 6891 (Entrez Gene) 170261 (OMIM) TAP2 (Alliance of Genome Resources)	Chr6 p21.32	Chr6:32821831-32838739 (-) GRCh38	allergic contact dermatitis Alzheimer's disease ankylosing spondylitis aspirin-induced respiratory disease cervical cancer cervix carcinoma dengue hemorrhagic fever diffuse scleroderma limited scleroderma lymphoproliferative syndrome multiple sclerosis psoriasis pulmonary tuberculosis reactive arthritis rheumatoid arthritis systemic lupus erythematosus tuberculoid leprosy type 1 diabetes mellitus	Q03519 (UniProt | EBI) NM_018833 (RefSeq)
mouse	Tap2	MGI:98484 (MGI) 21355 (Entrez Gene) Gene Tree Tap2 (Alliance of Genome Resources)	Chr17 17.98 cM	Chr17:34423453-34435295 (+) GRCm39		21355 (NCBI Gene Model) P36371 (UniProt | EBI) NM_011530 (RefSeq)
rat	Tap2	RGD:3818 (Rat Genome Database) 24812 (Entrez Gene) Tap2 (Alliance of Genome Resources)	Chr20 p12			P36372 (UniProt | EBI) NM_032056 (RefSeq)
zebrafish	tap2a	ZDB-GENE-030616-245 (Zebrafish Model Organism Database) 368771 (Entrez Gene) tap2a (Alliance of Genome Resources)	Chr19			NP_001006594 (RefSeq) NM_001006594 (RefSeq)
	tap2c	ZDB-GENE-990415-260 (Zebrafish Model Organism Database) 30695 (Entrez Gene) tap2c (Alliance of Genome Resources)	Chr19
	tap2t	ZDB-GENE-130531-48 (Zebrafish Model Organism Database) 556826 (Entrez Gene) tap2t (Alliance of Genome Resources)	Chr12			XP_021336011 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.