Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE6A	HGNC:8785 (HGNC) 5145 (Entrez Gene) 180071 (OMIM) PDE6A (Alliance of Genome Resources)	Chr5 q32	Chr5:149857953-149944793 (-) GRCh38	retinitis pigmentosa 43	P16499 (UniProt | EBI) NM_000440 (RefSeq)
mouse	Pde6a	MGI:97524 (MGI) 225600 (Entrez Gene) Gene Tree Pde6a (Alliance of Genome Resources)	Chr18 34.41 cM	Chr18:61353387-61422995 (+) GRCm39	retinitis pigmentosa	ENSMUSG00000024575 (Ensembl Gene Model) ENSMUSP00000025468 (Ensembl) ENSMUST00000025468 (Ensembl)
rat	Pde6a	RGD:1306835 (Rat Genome Database) 307401 (Entrez Gene) Pde6a (Alliance of Genome Resources)	Chr18 q12.1			NP_001100856 (RefSeq) NM_001107386 (RefSeq)
zebrafish	pde6a	ZDB-GENE-030616-42 (Zebrafish Model Organism Database) 368410 (Entrez Gene) pde6a (Alliance of Genome Resources)	Chr14			NP_001007161 (RefSeq) NM_001007160 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.