Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HBE1	HGNC:4830 (HGNC) 3046 (Entrez Gene) 142100 (OMIM) HBE1 (Alliance of Genome Resources)	Chr11 p15.4	Chr11:5268345-5505652 (-) GRCh38	sickle cell anemia	P02100 (UniProt | EBI) NM_005330 (RefSeq)
	HBG2	HGNC:4832 (HGNC) 3048 (Entrez Gene) 142250 (OMIM) HBG2 (Alliance of Genome Resources)	Chr11 p15.4	Chr11:5253188-5505605 (-) GRCh38	delta beta-thalassemia sickle cell anemia	P69892 (UniProt | EBI) NM_000184 (RefSeq)
mouse	Hbb-y	MGI:96027 (MGI) 15135 (Entrez Gene) Gene Tree Hbb-y (Alliance of Genome Resources)	Chr7 54.85 cM	Chr7:103500961-103502414 (-) GRCm39		15135 (NCBI Gene Model) P02104 (UniProt | EBI) NM_008221 (RefSeq)
rat	Hbe1	RGD:1305115 (Rat Genome Database) 293267 (Entrez Gene) Hbe1 (Alliance of Genome Resources)	Chr1 q32			NP_001008890 (RefSeq) NM_001008890 (RefSeq)
zebrafish	ba1l	ZDB-GENE-040901-4 (Zebrafish Model Organism Database) 504174 (Entrez Gene) ba1l (Alliance of Genome Resources)	Chr3			NP_001013045 (RefSeq) NM_001013027 (RefSeq)
	hbba1	ZDB-GENE-990415-18 (Zebrafish Model Organism Database) 30216 (Entrez Gene) hbba1 (Alliance of Genome Resources)	Chr3			Q90485 (UniProt | EBI) NM_131020 (RefSeq)
	hbba2	ZDB-GENE-040801-164 (Zebrafish Model Organism Database) 445037 (Entrez Gene) hbba2 (Alliance of Genome Resources)	Chr3			NP_001003431 (RefSeq) NM_001003431 (RefSeq)
	hbbe1.1	ZDB-GENE-030616-7 (Zebrafish Model Organism Database) 81538 (Entrez Gene) hbbe1.1 (Alliance of Genome Resources)	Chr3			NP_932339 (RefSeq) NM_198073 (RefSeq)
	hbbe1.2	ZDB-GENE-090501-3 (Zebrafish Model Organism Database) 793447 (Entrez Gene) hbbe1.2 (Alliance of Genome Resources)	Chr3			NP_001096600 (RefSeq) NM_001103130 (RefSeq)
	hbbe1.3	ZDB-GENE-131120-128 (Zebrafish Model Organism Database) 573653 (Entrez Gene) hbbe1.3 (Alliance of Genome Resources)	Chr3			NP_001352192 (RefSeq) NM_001365263 (RefSeq)
	hbbe2	ZDB-GENE-040702-1 (Zebrafish Model Organism Database) 405772 (Entrez Gene) hbbe2 (Alliance of Genome Resources)	Chr12			NP_998011 (RefSeq) NM_212846 (RefSeq)
	hbbe3	ZDB-GENE-980526-287 (Zebrafish Model Organism Database) 30596 (Entrez Gene) hbbe3 (Alliance of Genome Resources)	Chr12			NP_001015058 (RefSeq) NM_001015058 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.