Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TFPI	HGNC:11760 (HGNC) 7035 (Entrez Gene) 152310 (OMIM) TFPI (Alliance of Genome Resources)	Chr2 q32.1	Chr2:187464230-187565760 (-) GRCh38	B-lymphoblastic leukemia/lymphoma disseminated intravascular coagulation factor VIII deficiency liver cirrhosis myocardial infarction osteonecrosis protein S deficiency pulmonary fibrosis toxic shock syndrome transient cerebral ischemia	P10646 (UniProt | EBI) NM_006287 (RefSeq)
mouse	Tfpi	MGI:1095418 (MGI) 21788 (Entrez Gene) Gene Tree Tfpi (Alliance of Genome Resources)	Chr2 49.41 cM	Chr2:84263199-84307119 (-) GRCm39		21788 (NCBI Gene Model) O54819 (UniProt | EBI) NM_001177319 (RefSeq)
rat	Tfpi	RGD:61914 (Rat Genome Database) 29436 (Entrez Gene) Tfpi (Alliance of Genome Resources)	Chr3 q24			Q02445 (UniProt | EBI) NM_001177321 (RefSeq)
zebrafish	tfpia	ZDB-GENE-030711-1 (Zebrafish Model Organism Database) 359833 (Entrez Gene) tfpia (Alliance of Genome Resources)	Chr9			NP_001296732 (RefSeq) NM_182872 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.